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Application of 1H NMR Metabolomics to a Murine Model of Inflammatory Arthritis

Poster

Published: December 8, 2006

Application of 1H NMR Metabolomics to a Murine Model of Inflammatory Arthritis content piece image

The novel quantitative technique of "Targeted Profiling" of 1H 1D NMR data is applied to a unique model of rheumatoid arthritis. A number of candidate biomarkers not previously identified using NMR techniques are identified related to inflammation and immune response. The pharmaceutical relevance of several of these metabolites is discussed.