Application of 1H NMR Metabolomics to a Murine Model of Inflammatory Arthritis
Poster Dec 08, 2006
Reza Dowlatabadi, B. Joan Miller, Frank R. Jirik, Hans J. Vogel and Aalim M. Weljie
The novel quantitative technique of "Targeted Profiling" of 1H 1D NMR data is applied to a unique model of rheumatoid arthritis. A number of candidate biomarkers not previously identified using NMR techniques are identified related to inflammation and immune response. The pharmaceutical relevance of several of these metabolites is discussed.