Colony Forming Cell (CFC) Assays Predict for Increased Clinical Neutrophenia with Combination Therapies
Poster May 07, 2013
Dos Santos G, Mergaert A and Clarke E.
Combination therapies are being increasingly employed to treat diseases where single agents do not have the desired clinical benefit. There are a number of publications that cite the benefit of combination therapy over monotherapy in preventing disease progression.
During early drug discovery, the study of metabolism plays an essential role in determining which drug candidates move forward into development and later stages. As an alternative to traditional Data Dependent Acquisition (DDA), the use of MSE/All Ions Fragmentation (AIF) has become common in metabolite identification workflows for the analysis of metabolic hot spots. Here we present a solution for analysis of MSE/AlF in metID studies.READ MORE