Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery
• Sequences of droplets can be generated from 24 wells.
• Droplets can be merged pairwise.
• Nanoliter droplets can be split into picoliter droplets.
• Our system enables combinatorial screening in nanolitre volumes and we have demonstrated its application to drug screening whether in vitro or in vivo.
• Encapsulated S. Cerevisiae cells showed good growth for all cell strains overnight.
• C. elegans were also encapsulated and were stable in droplets overnight.