Drought Induced Increase in Quercetin Glycosides is Associated with Drought Resistance in a Novel White Clover Population
Poster Jul 22, 2011
Wouter L. Ballizany, Rainer W. Hofmann, Brent A. Barrett, Zulfi Jahufer
White clover is an important forage legume in temperate pastures, but does not have sufficient resistance against drought stress. Quercetin is a flavonol conferring plant sunscreen and anti-oxidant properties under UV-B stress with a trade-off of reduced biomass. An F1 full-sib cross between stress tolerant and stress sensitive white clover genotypes showed the ability to increase Q accumulation associated to maintenance of dry matter yield under a near wilting drought.
Despite the developments in conventional PCR, the complexity of multiplex Real Time PCR is still limited due to the lack of sufficient detection channels. To achieve high-end multiplexing capacity on standard Real Time PCR machines, Anapa Biotech has developed the MeltPlex® technology (see box on right).READ MORE
Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes. The majority of these are located in the intergenic or intragenic regions suggesting that the implicated variants may alter chromatin conformation. This, in turn, is likely to influence the expression of nearby or more remotely located genes to alter beta cell function. At present, however, detailed molecular and functional analyses are still lacking for most of these variants. We recently analysed one of these loci and mapped five causal variants in an islet-specific enhancer cluster within the STARD10 gene locus. Here, we aimed to understand how these causal variants influence b-cell function by alteration of the chromatin structure of enhancer clusterREAD MORE