Effect of Heat and Cold Treatment on Germination and Early Growth Stage of Terminal Heat Tolerant (WH 730) and Intolerant (RAJ 4014) Wheat Genotypes
Poster Jan 14, 2013
Om Prakash Gupta
The objective of the present study was to evaluate the effect of heat and cold stress on the germination potential and early growth stage of WH 730 (terminal heat tolerant) and Raj 4014 (terminal heat intolerant) wheat genotypes identified from previous field experiments to develop a platform for screening the genotypes for terminal heat tolerance at seedling stage.
Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes. The majority of these are located in the intergenic or intragenic regions suggesting that the implicated variants may alter chromatin conformation. This, in turn, is likely to influence the expression of nearby or more remotely located genes to alter beta cell function. At present, however, detailed molecular and functional analyses are still lacking for most of these variants. We recently analysed one of these loci and mapped five causal variants in an islet-specific enhancer cluster within the STARD10 gene locus. Here, we aimed to understand how these causal variants influence b-cell function by alteration of the chromatin structure of enhancer clusterREAD MORE
Early life stress (ELS) is highly associated with development of psychopathology
and mood disorders in adulthood. Genetic studies have identified variation in the gene calcium voltage-gated channel subunit alpha1C (CACNA1C) to increase risk for several psychiatric disorders. This poster assessed the expression of Cacna1c following prepubertal stress.