Enhanced method development capabilities with automated SPME extraction optimization
Poster Jun 13, 2013
Roger Pearson1; Douglas Doster1; Ken Rice1; Scott Klasen1; Tom Flug2; Guenter Boehm2
• SPME (solid phase micro extraction; s. ref 1) is an analyte enrichment method commonly used for the analysis of gaseous or liquid samples in conjunction with gas chromatography/mass spectrometry.
• An important part of method optimization is the selection of the appropriate fiber. This normally requires the manual changing of fibers. In practice, little fiber optimization work is actually done and most methods used rely on analyst experience.
• A new type of robotic sample handler allows for the automatic change of tools. This opens the possibility for the automated selection of the best suited SPME fiber as well as the optimization of key process parameters.