Ensuring the Quality of Registered Compounds in a Drug Discovery Environment – A Multidisciplinary Approach
Poster May 05, 2011
Ryan Sasaki and Tara Sinclair
In addition, it has provided a means to apply analytical review, with minimal staffing, to entire collections of compounds which would otherwise not be possible. The system identifies a manageable subset of the entire compound collection for an analytical specialist, eliminating the need to look at compounds with a high degree of confidence and concentrate on those more likely to be of issue. Simplicity has been the key to its effective and growing use in the organization. The benefits of this system to synthetic chemists are clear—the amount of additional effort on behalf of the chemists’ workflow is negligible but provides a plethora of useful information, including an overall assessment of their compound tentative assignments. With this combination, user acceptance and trust from the medicinal chemistry community was gained. This poster will focus mainly on the addition of an NMR verification filter using commercial NMR software to existing automated in-house HPLC and LC/MS assessment tools.
Automating Mass Spectrometry-Based Quantitative Glycomics using Tandem Mass Tag (TMT) Reagents with SimGlycanPoster
One of the emerging trends in glycomics research is the innovation related to accurate MS based quantitative analysis of glycans.READ MORE
RAMclust/RAMsearch: efficient post-XCMS feature clustering and annotation of MS-based metabolomics datasetsPoster
Chromatographically coupled mass spectrometry is a powerful tool for profiling, semi-quantitatively or quantitatively, a breadth of small molecules with sensitivity and selectivity.READ MORE
Highly Accurate HCV Genotyping by Targeted Next Generation SequencingPoster
The recent fast advancement of next generation sequencing (NGS) technologies allowing for unprecedented speed and accuracy in analyzing viral genomes are opening new ways to further improve diagnostic genotyping of HCV.
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Tackling the Challenges of Artificial Intelligence
News Jan 19, 2017