Experimental Evolution in Diatoms - Thermal longterm acclimation in two model diatom species

Poster   Nov 24, 2014

 
Experimental Evolution in Diatoms - Thermal longterm acclimation in two model diatom species
 
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Katrin Schmidt1, Sinéad Collins2, Thomas Mock1

 
 

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License

 
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We found a distinct subpopulation of Tregs within BMSCs. Tregs and BMSCs in co-culture conferred neuroprotection that varied in a dose-dependent manner. Tregs minimized stem cell production of IL-6, a pro-inflammatory cytokine, and inhibited BMSC secretion of FGF-beta, a cytokine related to BMSC proliferation and differentiation. The ratio of Tregs found natively in BMSCs is optimally adapted to provide the maximum neuroprotective benefit of stem cell treatment after ischemic stroke.

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