We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.


Fixed-Width Binning, Variable-Width Binning or No Binning: A Study of Different Binning Methods in NMR-based Metabolomics Analysis

In the multivariate analysis of NMR-based metabolomics data, small variations in the resonance position of the individual peaks caused by experimental and instrument induced variations can adversely impact the PCA results. Techniques to address the NMR peak misalignment issue include the commonly used binning or bucketing, and the more advanced algorithms that aim at shifting the individual peaks to reach a better alignment across the spectra.