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Hematopoietic Stem Cell Transplantation: Are We There Yet?

Poster   Nov 08, 2014

 
Hematopoietic Stem Cell Transplantation: Are We There Yet?
 
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Shalmali Pendse, Anuradha Vaidya

 
 

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License

 
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5 Steps to Multiplexed Fluorescent Western Blotting

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Download this free poster for step-by-step advice on troubleshooting your western blotting for protein analysis.

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PASEF Enhances the Speed, Sensitivity and Selectivity of Label-free Quantification

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Download this poster to learn how an adapted version of PEAKS™ enables identifications and label-free quantification from PASEF runs and enhances the speed, sensitivity and selectivity of label-free quantification.

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Characterization of a Type 2 diabetes-associated islet-specific enhancer cluster in STARD10 by genome editing of EndoC-βH1 cells

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Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes. The majority of these are located in the intergenic or intragenic regions suggesting that the implicated variants may alter chromatin conformation. This, in turn, is likely to influence the expression of nearby or more remotely located genes to alter beta cell function. At present, however, detailed molecular and functional analyses are still lacking for most of these variants. We recently analysed one of these loci and mapped five causal variants in an islet-specific enhancer cluster within the STARD10 gene locus. Here, we aimed to understand how these causal variants influence b-cell function by alteration of the chromatin structure of enhancer cluster

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