High Throughput Microwave Synthesis of Metal Organic Framework (MOF) Libraries
Poster Jan 25, 2008
Neil L. Campbell, Jake Grace, Richard W. Dewson, Jean-Noel Rebilly, Darren Bradshaw, Ben Carter, Andrew I. Cooper and Mathew J. Rosseinsky
Metal-organic frameworks (MOFs) are an emerging class of new nano-porous materials of considerable academic and industrial interest due to their potential applications in gas storagechiral separations and catalysis. MOFs are prepared from the self-assembly of metal ions (nodes) and organic ligands (spacers), where the structural topology of the resulting crystalline frameworks is driven by the co-ordination preferences of these nodes and spacers. MOFs offer opportunities not available to more classical sorbents such as the aluminosilicate zeolites and activated carbons as their pore sizes and functionality are more readily tuneable. A rapid microwave process for the synthesis of MOFs has been developed and implemented by the Centre for Materials Discovery (CMD), which is over 100 times faster compared to conventional synthesis methods. Libraries of new MOF materials have since been synthesised and characterised using high throughput robotic formulation platforms and analytical equipment.
New Biotransformation Prediction Engine Integrated into a Metabolite Identification SolutionPoster
Here we present a new prediction algorithm that determines the likelihood of biotransformation reactions, and subsequent metabolite identification, within an automated processing routine.READ MORE
NanoBRET™ Assays for Monitoring Protein Interactions in Living CellsPoster
NanoBRET PPI System is composed of two components.
NanoBRET offers improved S:B over other BRET assays.
NanoBRET provides sensitive live-cell method to study protein interactions.