Identification of Genomic and Proteomic Signatures in Lymphomas by Inducible shRNA
Poster Feb 06, 2006
Roberto Piva, Elisa Pellegrino, Michela Mattioli, Claudia Voena, Chiara Conte, Francesco Boccalatte, Chiara Ambrogio, Andrea Manazza, Antonio Neri, Roberto Chiarle and Giorgio Inghirami
AbstractThe combination of RNA interference with gene expression profiling and proteomic analysis represent a powerful tool to characterize the signaling network mediating tumorigenesis and maintenance of ALK positive lymphomas and to individuate suitable targets for a therapeutic intervention.
Despite the developments in conventional PCR, the complexity of multiplex Real Time PCR is still limited due to the lack of sufficient detection channels. To achieve high-end multiplexing capacity on standard Real Time PCR machines, Anapa Biotech has developed the MeltPlex® technology (see box on right).READ MORE