Investigating the Effects of Fructose Consumption and Inadequate Copper Intake on Nonalcoholic Fatty Liver Disease
Poster Mar 22, 2017
David E. Alonso, Biyun Shi, Ming Song, Xinmin Yin, Xiaoli Wei, Michelle Page, Joe Binkley, Craig McClain, and Xiang Zhang
Inflammation, oxidative stress, dyslipidemia, insulin resistance, and obesity are key clinical risk factors for the progression of non-alcoholic fatty liver disease (NAFLD). Interactions between diet, liver, and immune system play an important role in this disease. Increased fructose consumption and inadequate copper intake are two critical factors that may contribute to metabolic syndrome and lead to the development of diseases such as NAFLD. For example, increased consumption of high fructose corn syrup has been associated with liver fibrosis severity in subjects with NAFLD.
Metabolomics is a viable method for identifying compounds associated with NAFLD. In this investigation, high-quality data facilitate the identification of key metabolites differentiating normal versus diseased species.
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We used modern-day, high-resolution time-of-flight mass spectrometry (HRT) and powerful processing software to quickly and confidently identify compounds in urine.READ MORE
Screening Medical Marijuana for Pesticides by GC-MS/MSPoster
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The method allows for automated determination of total fat content and quantitative analysis of saturated and unsaturated cis- and trans- fatty acids of different chocolate products.READ MORE
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14th Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology Industry
Sep 19 - Sep 23, 2017