Laser Welded Microfluidic Plasma Seperation Unit with On-Chip Pressure Conversion
Poster Apr 04, 2012
Thomas Brettschneider, Christian Dorrer, Roland Zengerle and Martina Daub
-Separation of plasma from full blood is necessary for many diagnostic assays e.g. ELISA
-Existing microfluidic solutions usually require well-defined flow rates and pressure drops provided by external driving unit
-Here, a low-cost, polymer-based system for the separation of plasma is presented. This system contains a membrane and a microfluidic component for converting an external pressure to a defined driving pressure on chip.
The immune system is a striking example of an integrated information system, engaged in coordinated host-protective activities. Organs-on-chip approach (OOC) models allow the direct simultaneous observation of hundreds of different cells, moving, interacting and responding to signals coming from the microenvironment nearby, that give access to a number of parameters describing the system that must be properly measured and elaborated.READ MORE