Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications

Poster Feb 28, 2015

View Poster

Daniel Czurratis*, Yvonne Beyl*, Sven Zinober*, Franz Lärmer*, Roland Zengerle**

A new concept for long-term reagent storage for Lab-on-a-Chip (LoC) devices is described. Here we present a polymer multilayer stack with integrated stick packs for long-term storage of several liquid reagents, which are necessary for many diagnostic applications. Stick packs are widely used in packaging industry for storing solids and liquids for long time. The storage concept fulfills two main requirements: First, a long-term storage of reagents in stick packs without significant losses and interaction with sur-roundings, second, on demand releasing of liquids, which is realized by pushing a membrane against the stick pack through pneumatic pressure. This concept enables long-term on-chip storage of liquid reagents at room temperature and allows an easy implementation in different LoC devices.

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License

View Poster

OTHER POSTERS

Profiling Personal Air Pollutant Exposures Using a Wearable Non-Selective Passive Wristband

Poster

Characterizing cumulative exposure to air pollutant mixtures is a critical step in understanding disease development. The Fresh Air wristband was tested as a personal exposure assessment tool with promising results.

P450 Induction in Cryopreserved Hepatocytes from PXR and CAR Nuclear Receptor Knock-out Rats

Poster

The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that regulate the expression of phase I (cytochrome P450s), phase II metabolizing enzymes and transporter genes in response to xenobiotics, including prescription drugs.

A new method for generating arrayed RNAi screening tools for any organism

Poster

RNA interference (RNAi) using small interfering RNAs (siRNAs) is an important technology for down-regulation of gene expression and a powerful tool to study cellular processes and pathways. Previously, large collections of siRNAs were available only for traditional experimental model systems, such as human and mouse, and predominantly provided as chemically synthesized libraries.

Like what you just read? You can find similar content on the communities below.

Diagnostics

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free