Low-cost “Plug & Play” On-Chip Valve and Pump for Thermoplastic Microfluidics
Poster Nov 18, 2013
Mousavi Shaegh Seyed Ali, Wang Zhenfeng, Toh Guek Geok, Soh Yong Chear
On-chip valving, which has been widely applied in polydimethylsiloxane (PDMS) microfluidics is difficult to migrate to thermoplastic microfluidics which is the better candidate in many lab-on-a chip and diagnostics applications.
The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that regulate the expression of phase I (cytochrome P450s), phase II metabolizing enzymes and transporter genes in response to xenobiotics, including prescription drugs.READ MORE
RNA interference (RNAi) using small interfering RNAs (siRNAs) is an important technology for down-regulation of gene expression and a powerful tool to study cellular processes and pathways. Previously, large collections of siRNAs were available only for traditional experimental model systems, such as human and mouse, and predominantly provided as chemically synthesized libraries.READ MORE