Method Optimization for Comprehensive Characterization of Petroleum with High Resolution Time-of-Flight Mass Spectrometry Platforms
Poster Jun 06, 2014
Clecio F. Klitzke, David Alonso, Kevin Siek, Elizabeth Humston-Fulmer, Joe Binkley, Jeff Patrick
Petroleum is the most complex matrix in nature, constituted by many thousands of compounds. As such, petroleum analysis presents an analytical challenge, and for mass spectrometric analysis we need equipment with high resolving power and high mass accuracy. The matrix complexity and characterization needs demand analytical solutions that will identify individual components (micro-) while also providing differential information on contributions from key functional group contributions (macro-characterization). Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) is the gold standard for comprehensive analysis of crude oil and petroleomic studies and offers both analytical capabilities mentioned. An alternative to FT-ICR MS is time-of-flight mass spectrometry (TOFMS), which offers continuous full range non-skewed mass spectral information and fast acquisition rates ideal for analyte identification of complex mixtures. TOFMS also offers the significant advantage of being readily interfaced to GC and providing acquisition rates compatible with GC. Advances in the resolution of TOFMS provide an alternative for most routine petroleomic MS studies using ESI, APCI, EI, and CI.
Overcoming the Challenges of Analysing Ionic Polar Pesticides in FoodPoster
Here, the novel application of the Waters’ Torus DEA column is presented, showing the improved performance of a UPLC-MS/MS method for the underivatised
analysis of glyphosate and a selection of other anionic pesticides.
LC-SWATH/MS Metabolomics Platform with Hyphenation of Extraction for the Analysis of Polar and Non-polar Metabolites in Biological SamplesPoster
Automated robotic sample preparation with hyphenated dual LC-SWATH/MS analysis for lipids and polar metabolites.
The Use of Pyrolysis/GCMS and Newly Developed Libraries to assist in Characterizing Complex Polymeric SamplesPoster
Pyrolysis-GC/MS is an effective tool in introducing and analyzing polymers. But since the polymer must be broken down to volatile segments in order to be sent to the GC, identification by the Mass Spec does not look at the original polymer, but only the fragments. This poster will look at a unique library designed to work with the existing NIST library, however contains averaged spectra of pyrolyzed polymers so it can be used to directly identify the original polymer sample.READ MORE