Miniaturisation of Liquid Handling Procedures for High Throughput Sequencing
Poster Aug 30, 2005
Joe Graham, Sheila Fisher, Tracey Honan, Susan Faro and Aoife Gallagher
Deerac Fluidics Equator™ products are designed to fit a wide range of applications requiring low volume liquid handling. The products have recently been installed as part of the high throughput sequencing production process at the Broad Institute in Boston, MA, USA (formerly the Whitehead Center for Genome Research). The Genome Sequencing and Analysis program at the Broad Institute places emphasis on the development of scalable methods employing automated laboratory procedures and informatics systems. The current rate of sequencing is over 40 million lanes per year, sequencing human, mouse, and other genomes.
This poster will describe the current process employed by Broad Institute, highlighting where the Equator™ has played a vital role in performance enhancement and cost reduction, enabling the Broad Institute to retain its position as the world’s leading genome research institute.
Psychiatric Risk Gene Cacna1c and Early Life Stress: Potential Gene-Environment interactions?Poster
Early life stress (ELS) is highly associated with development of psychopathology
and mood disorders in adulthood. Genetic studies have identified variation in the gene calcium voltage-gated channel subunit alpha1C (CACNA1C) to increase risk for several psychiatric disorders. This poster assessed the expression of Cacna1c following prepubertal stress.
Correlations among the Toddler Gut Microbiome and Health Status VariablesPoster
Establishment and succession of the human microbiome begins at birth and microbial composition adapts alongside human development and growth. Development of a healthy signature microbial community has significant effects on health.This study followed 18 very low birth weight (VLBW) infants, measured initially in the from Neonatal Intensive Care Unit (NICU), at the age of two to three years old.READ MORE
A Computational Model of Mood and Future ProspectsPoster
Mood disorders are characterized by changes in reaction to positive events, but studies examining mood in gambling have suggested these changes may not be different from control. Interrogating mood changes with a computational model may give insight into disorders like depression.READ MORE
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2nd Annual Artificial Intelligence in Drug Development Congress
Sep 20 - Sep 21, 2018