MONOCLONAL ANTIBODIES - A NEW THERAPEUTIC STRATEGY OF AUTO IMMUNE DISEASE
Poster Nov 27, 2017
Krunal Jasani, Drashti Patel, Ruchita Desai
Monoclonal antibodies are monospecific antibodies which are made from identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope. Monoclonal antibodies are currently used for many diagnostic and therapeutic applications. Furthermore, strategies of cell engineering, although still mostly based on trial-and-error experimentation and not in standard protocols, hold great interest to improve cell growth and productivity, as well as product quality in the future.
Multiplexing cell-based assays is possible using 3D culture models that are larger and more complex than monolayers
Real-time detection methods to measure live or dead cells provide much flexibility for multiplexing
All multiplexed assay combinations should be verified using appropriate controls for each 3D cell culture model.