MONOCLONAL ANTIBODIES - A NEW THERAPEUTIC STRATEGY OF AUTO IMMUNE DISEASE
Poster Nov 27, 2017
Krunal Jasani, Drashti Patel, Ruchita Desai
Monoclonal antibodies are monospecific antibodies which are made from identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope. Monoclonal antibodies are currently used for many diagnostic and therapeutic applications. Furthermore, strategies of cell engineering, although still mostly based on trial-and-error experimentation and not in standard protocols, hold great interest to improve cell growth and productivity, as well as product quality in the future.
Primary Human Hepatocyte (PHH) culture provides the closest in vitro model to human liver that can produce a metabolic profile of a given drug very similar to that found in vivo. Recently we have developed an easy-to-assemble user-friendly in vitro Primary Human Hepatocyte (PHH) 3D-spheroid modelREAD MORE