Over-representation of Proteins Identified as Disease Biomarkers and their Relation to Post-Mortem Events
Poster Sep 17, 2013
B. Orback, K. Kultima, M. Borén, M. Söderquist and K. Sköld
This poster reports a remarkable overlap between proteins commonly identified as changing in 2D-GE proteomic studies and those found to change post-mortem. Proteins with one or more phosphorylation sites are of particular interest since they appear to be overrepresented in this group.
The approach detailed may help differentiate true biomarkers from those proteins found in any situation where cells are under stress.
Application of Solid Phase Micro Extraction (SPME) and On‐Fiber Derivatization to Detect Precursors of Biomolecules in the study of Proto‐metabolismPoster
In the studies of origins of life, plausible synthetic reaction pathways to form biological relevant molecules, or building blocks of proto‐bilayer lipids, protein, RNA, and DNA in the primitive environment have been investigated intensively.READ MORE
Assessment of Oral LISPRO Treatment in Ameliorating Amyloid and Tau Pathology in Transgenic Alzheimer’s Mice ModelPoster
Ionic co-crystals of lithium salicylate with organic proline (LISPRO) showed better safety and pharmacokinetic profile of lithium in plasma and brain of wild-type and transgenic Alzheimer mice model compared to lithium salts.READ MORE
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