Pathogenesis and Clinical Presentation of Throat Candidiasis in Durrës area, Albania
Poster Mar 17, 2015
PhD Cand. Anisa Liti, Prof. Dr. Margarita Hysko
Candidiasis, commonly called yeast infection or thrush, is a fungal infection of any of the Candida spp., of which Candida albicans is probably the most common. In most individuals, C. albicans is a member of the normal human microbiome, resides as a lifelong, harmless commensal. Under certain circumstances, however, C. albicans can cause infections that range from superficial infections of the skin to life-threatening systemic infections. C. albicans is able to switch reversibly between yeast and hyphal growth forms in response to environmental cues. In this study, 1317 throat sampes were examined. These samples were recived by the Microbiology Laboratory of DRSH, Durrës, Albania, collected between April 2012 and December 2013.
We focused our attention on the prevalence of C. albicans in throat and it’s relation to sex, seasons and age.
It resulted that 372 out of 1317 samples were infected by C. albicans throat infections.
The infection was mostly prevalent in women, 63% out of all positive results.
The age group most affected were 76-90 years old and 46-60 years old.
We found this infection highly prevalent in autumn with 26% of positive results.
When there is a need to quickly analyze samples using a number of different PCR assays, it is likely that optimal conditions for each assay will not be the same. First, different assays often will require different annealing temperatures for their primers. In addition, amplicons may be designed to be of different lengths and therefore require varying durations of the extension step.READ MORE