Protein Microarrays for Characterisation of the Bacillus anthracis ‘infectome’
Poster Dec 18, 2013
Stephen Kidd, Karen Kempsell, Rebecca Ingram, Pierre Watteau, Daniel Altmann, Michael Elmore, Sue Charlton, Bassam Hallis and Richard Vipond
Bacillus anthracis is a Gram-positive spore-forming, rod-shaped bacterium that is the etiological agent of the zoonotic disease Anthrax. Reservoirs for anthrax are wild and domestic grass-eating animals, most commonly sheep, goats and cattle and their proximity to humans within an agricultural setting can cause infection and disease. Disease may also be contracted through either direct contact with infected animals or through contact with animal by-products such as wool, skins or bone meal, where spores can survive in the environment for decades. Disease can occur when spores enter the body through breaks in the skin, via ingestion or by inhalation and has a number of clinical presentations. The Anthrax bacillus expresses a number of proteins responsible for the pathology of disease, including the protein toxins lethal factor (LF), oedema factor (OA) and protective antigen (PA). Other proteins are likely to be expressed during infection, which may contribute to the disease process.
Overcoming the Challenges of Analysing Ionic Polar Pesticides in FoodPoster
Here, the novel application of the Waters’ Torus DEA column is presented, showing the improved performance of a UPLC-MS/MS method for the underivatised
analysis of glyphosate and a selection of other anionic pesticides.
A New Tool for the Automated Sample Preparation of Whole Blood Samples by LC-MS using a Commercial AutosamplerPoster
Automated sample preparation reduces the costs per sample and minimizes sample handling errors. Usually expensive and highly specialized pipetting robots are used. However, most of these systems are not designed with a direct interface for LC-MS applications. In addition common pipetting systems are not optimized for smaller scale sample series. Here we present a new tool for liquid handling of whole blood samples and direct sample injection.READ MORE
Fully automated sample preparation for the determination of plasticizers in PVC from food contact materials and toysPoster
The poster outlines a comprehensive, fully automated analysis of plasticizers in toys and food stuff.READ MORE