Psychiatric Risk Gene Cacna1c and Early Life Stress: Potential Gene-Environment interactions?
Poster May 22, 2018
Moon A, Haan N, Brydges N, Thomas K, Hall J
Early life stress (ELS) is highly associated with development of psychopathology and mood disorders in adulthood.
Genetic studies have identified variation in the gene calcium voltage-gated channel subunit alpha1C (CACNA1C) to increase risk for several psychiatric disorders.
This poster assesses the expression of Cacna1c following prepubertal stress.
When there is a need to quickly analyze samples using a number of different PCR assays, it is likely that optimal conditions for each assay will not be the same. First, different assays often will require different annealing temperatures for their primers. In addition, amplicons may be designed to be of different lengths and therefore require varying durations of the extension step.READ MORE