Putative Genes Identified on Two Growth Conditions of G. boninense
Poster Jan 10, 2015
Jayanthi N, Abrizah O, Low ETL, O-Abdullah M, Hogan M, Cuomo CA, Desjardins C, Abdul Manaf MA, Rajinder S, Birren B and Ravigadevi S
Ganoderma boninense is an infamous facultative fungal pathogen that has been the causal agent of basal stem rot (BSR) disease in oil palm (Elaeis guineensis). The disease has caused the deaths of palms as young as 12-24 months and has been a serious threat to the oil palm industry in South East Asian countries, especially Malaysia and Indonesia. The acreage of plantation infected with BSR disease in Peninsular Malaysia was recorded to be about 400,000 hectares. Fundamental studies on G. boninense are limited, especially on the genes involved in pathogenicity. Therefore, to further understand the fundamental biology of the genes involved in degradation, the mycelial of G. boninense was cultivated on two different mediums, fresh potato dextrose agar (PDA) in petri plates as the standard growth media (PER71) and rubber wood blocks (PER71-47) as the comparative.
Characterization of a Type 2 diabetes-associated islet-specific enhancer cluster in STARD10 by genome editing of EndoC-βH1 cellsPoster
Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes. The majority of these are located in the intergenic or intragenic regions suggesting that the implicated variants may alter chromatin conformation. This, in turn, is likely to influence the expression of nearby or more remotely located genes to alter beta cell function. At present, however, detailed molecular and functional analyses are still lacking for most of these variants. We recently analysed one of these loci and mapped five causal variants in an islet-specific enhancer cluster within the STARD10 gene locus. Here, we aimed to understand how these causal variants influence b-cell function by alteration of the chromatin structure of enhancer clusterREAD MORE
Psychiatric Risk Gene Cacna1c and Early Life Stress: Potential Gene-Environment interactions?Poster
Early life stress (ELS) is highly associated with development of psychopathology
and mood disorders in adulthood. Genetic studies have identified variation in the gene calcium voltage-gated channel subunit alpha1C (CACNA1C) to increase risk for several psychiatric disorders. This poster assessed the expression of Cacna1c following prepubertal stress.
Performance of the D5000 and High Sensitivity D5000 ScreenTape Assays for the 4200 TapeStation SystemPoster
Here, we focus on quantification, sizing, and sensitivity of both D5000 ScreenTape assays.READ MORE
15th International Conference and Exhibition on Metabolomics & Systems
Apr 29 - Apr 30, 2019