Quercetin Accumulation is Associated with Drought Resistance in White Clover
Poster Aug 17, 2011
Ballizany, W.L 1, Hofmann, R.W. 1, Jahufer, M.Z.Z. 2, Barrett, B.A. 2
White clover is an important pasture legume, but growth is often strongly reduced under summer drought. Abiotic stress is mediated by the induced production of flavonoids. At the individual genotype level, increased flavonol (quercetin) accumulation in response to water deficit stress is positively associated to retaining higher levels of dry matter production. Selected genotypes from this study show promise for plant breeding trials focussing on increasing yield in dryland environments.
Despite the developments in conventional PCR, the complexity of multiplex Real Time PCR is still limited due to the lack of sufficient detection channels. To achieve high-end multiplexing capacity on standard Real Time PCR machines, Anapa Biotech has developed the MeltPlex® technology (see box on right).READ MORE
Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes. The majority of these are located in the intergenic or intragenic regions suggesting that the implicated variants may alter chromatin conformation. This, in turn, is likely to influence the expression of nearby or more remotely located genes to alter beta cell function. At present, however, detailed molecular and functional analyses are still lacking for most of these variants. We recently analysed one of these loci and mapped five causal variants in an islet-specific enhancer cluster within the STARD10 gene locus. Here, we aimed to understand how these causal variants influence b-cell function by alteration of the chromatin structure of enhancer clusterREAD MORE