Screening Medical Marijuana for Pesticides by GC-MS/MS
Di Wang, Laura Chambers, William Lipps, Zhuangzhi ‘Max’ Wang, Robert Clifford; Shimadzu Scientific Instruments, Columbia, MD, USA
Since medical marijuana (MM) was legalized in California in 1996, 23 states and Washington, D.C. have passed laws allowing its use for a variety of medical conditions. From a consumer safety point-of-view, quantitation of the pesticide residues in MM products has begun to attract wide interest. There are several problems associated with analysis of pesticide residues in MM. First and foremost, there are very few regulatory guidelines established to define which pesticides to include or what the detection limits should be, and secondly the matrix is very complex with significant interferences. Finally, sample load is growing exponentially, so the chosen method must be quick and easy to perform. Trace level pesticide analysis in complex food matrices have been done for many years with similar challenges, thus many of the analytical protocols emerging for the MM matrix are based on these well-established techniques.
Triple-quadrupole GC-MS/MS operated in MRM mode provides significant sensitivity and selectivity, but method development can be expensive and time consuming. This poster describes streamlined method development process for analysis of pesticide residues in MM using a QuEChERS sample preparation method, followed by GC-MS/MS detection and quantitation.
Application of Solid Phase Micro Extraction (SPME) and On‐Fiber Derivatization to Detect Precursors of Biomolecules in the study of Proto‐metabolismPoster
In the studies of origins of life, plausible synthetic reaction pathways to form biological relevant molecules, or building blocks of proto‐bilayer lipids, protein, RNA, and DNA in the primitive environment have been investigated intensively.READ MORE
A New Tool for the Automated Sample Preparation of Whole Blood Samples by LC-MS using a Commercial AutosamplerPoster
Automated sample preparation reduces the costs per sample and minimizes sample handling errors. Usually expensive and highly specialized pipetting robots are used. However, most of these systems are not designed with a direct interface for LC-MS applications. In addition common pipetting systems are not optimized for smaller scale sample series. Here we present a new tool for liquid handling of whole blood samples and direct sample injection.
Multi-Residue Pesticide Analysis in Food Matrices Using Ultivo Triple Quad LC/MSPoster
Regulatory agencies have set maximum residue levels for hundreds of pesticides and their metabolites in foods.READ MORE
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10th Edition of International Conference on Structural Biology 2018
Mar 15 - Mar 17, 2018