Spice Wars- Are You Battle Ready? Analysis of Synthetic Cannabinoids via Gas Chromatography—High Resolution Time-of-Flight Mass Spectrometry

Detection of designer drugs in clinical and forensic toxicology settings are complicated by:
-Novelty of synthetic drugs (Moving targets)
-Chemical diversity of compounds
-Complexity of herbal samples (Botanical matrix, impurities, etc.)
-Inappropriate sample preparation methodology
-Unsuitable instrument analysis protocol
-Lack of standards and/or absence of library spectra
Solution:
-Gas Chromatography–High Resolution (R>25,000), accurate mass (<1 ppm), time-of-flight mass spectrometry (GC-HRT)
-High Resolution CI-Source (HR-CI) for complementary EI and CI data acquisition
-Comprehensive data that can be interrogated multiple times as new drugs are discovered
-Novelty of synthetic drugs (Moving targets)
-Chemical diversity of compounds
-Complexity of herbal samples (Botanical matrix, impurities, etc.)
-Inappropriate sample preparation methodology
-Unsuitable instrument analysis protocol
-Lack of standards and/or absence of library spectra
Solution:
-Gas Chromatography–High Resolution (R>25,000), accurate mass (<1 ppm), time-of-flight mass spectrometry (GC-HRT)
-High Resolution CI-Source (HR-CI) for complementary EI and CI data acquisition
-Comprehensive data that can be interrogated multiple times as new drugs are discovered
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