Stealth-Adapted Viruses and Viteria: Insights into Virus Construction, Replication and Potential Therapies
Poster Dec 11, 2013
W. John Martin
Stealth-adaptation is a mechanism that allows cytopathic viruses to evade immune elimination through the deletion of genes coding the major antigens targeted by the cellular immune system. A prototype stealth-adapted virus, repeatedly cultured from a patient with chronic fatigue syndrome (CFS) was cloned and partially sequenced. It has a fragmented, genetically unstable, genome.
Despite the developments in conventional PCR, the complexity of multiplex Real Time PCR is still limited due to the lack of sufficient detection channels. To achieve high-end multiplexing capacity on standard Real Time PCR machines, Anapa Biotech has developed the MeltPlex® technology (see box on right).READ MORE