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Poster

The Challenges of Genetic Testing in Patients Diagnosed with Breast Cancer; The Kent Oncology Centre Experience

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Poster

The Challenges of Genetic Testing in Patients Diagnosed with Breast Cancer; The Kent Oncology Centre Experience

Background:

• NICE guidelines advise to offer genetic testing for BRCA mutations if the risk of being a BRCA carrier is over 10%

• In patients with a suggestive personal and/or family history, a specific predisposing gene is identified in <30% of cases.

• A BRCA1 pathogenic mutation found in 45/308 participants in the TNT trial

• Women with triple negative BrCa <50years had a 20% BRCA1 mutation prevalence

Aims:

• To document the number of new pathogenic mutation carriers identified

• To estimate the expected number of carriers based on Family History and presentation

• To highlight the gap in case identification and offer solutions to
optimise pathways
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