The Mesenchymal Stem Cells Bioengineered Tissue Using Cobalt-60 Radiation
Poster Feb 16, 2012
Mosca, RC., Isaac, C., Mathor, MB
Here scientists propose an experimental model where the replenishment of the depleted stem cell compartment of human skin may be explored using a dermal epidermal equivalent system, composed by 50 Gy irradiated extracellular collagen matrix, adipocytes derived mesenchymal stem cells (ADSCs) and normal keratinocytes.
Histone Deacetylase 6 (HDAC6) As A Therapeutic Target in Chronic Lymphocytic LeukemiaPoster
This study investigates the role of histone deacetylase 6 (HDAC6) in chronic lymphocytic leukemia and establishes it as a novel therapeutic target for the treatment of this disease.READ MORE
Inhibition of The Auto-inflammation Suppressor Protein ISG15 Triggers Preeclampsia by Blocking Trophoblast Migration and InvasionPoster
In summary, ISG15 expression levels are crucial for trophoblast morphology and function (migration/invasion). By blocking trophoblast invasion, reduced ISG15 levels could contribute to impaired spiral artery transformation that reduces utero-placental blood flow in preeclampsia. Thus, agents inducing ISG15 expression are likely to be therapeutic in preeclampsia.
Comparison of CD45+ Depletion Methods for Enrichment of Disseminated Tumor Cells in Bone Marrow SamplesPoster
Comparison of CD45+ depletion methods for enrichment of disseminated tumor cells in bone marrow samples.READ MORE