We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
Jet-Printing Microfluidic Devices on Demand
Product News

Jet-Printing Microfluidic Devices on Demand

Jet-Printing Microfluidic Devices on Demand
Product News

Jet-Printing Microfluidic Devices on Demand

Credit: Iota Sciences

Want a FREE PDF version of This Product News?

Complete the form below and we will email you a PDF version of "Jet-Printing Microfluidic Devices on Demand "

First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

Jet-printing microfluidic devices on demand1 – a new paper from engineering and biomedical scientists at the University of Oxford and spin-out company iotaSciences Ltd – describes a game-changing method to generate cell-friendly microfluidic devices on demand. This innovative protocol offers significant benefits to biology and biomedicine, enabling simple, contactless fabrication of microfluidic circuits in minutes – almost as quickly as the circuit pattern can be drawn on paper – using truly cell-friendly materials; standard Petri dishes and culture media.

The pioneering jet-printing method stems from the recognition that gravity becomes irrelevant at the microscale. In the everyday world, objects are invariably made with solids; building complex structures out of liquids, which would collapse into puddles and drain away, is not feasible. Using microjets to fabricate microfluidic devices takes advantage of the interfacial forces that dominate in the microworld. In this paper, the method was used to successfully clone cells by limiting dilution in a way that beats the Poisson limit, to subculture adherent cells, and to feed arrays of cells continuously for a week in sub-microliter chambers. Liquid flows were driven through conduits with and without external pumps, and circuits reconfigured to open and close ‘fluidic valves’ at will. The diversity and flexibility of this approach is expected to lead to widespread adoption of the technique for a variety of applications in biomedicine. 

Reference: Soitu C, Stovall‐Kurtz N, Deroy C, Castrejón‐Pita AA, Cook PR, Walsh EJ. Jet‐Printing Microfluidic Devices on Demand. Adv. Sci. 2020. doi:10.1002/advs.202001854


Advertisement