Kinexus Announces Launch of KiNET Functional Proteomics Database
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Kinexus Bioinformatics Corporation has announced the availability of its Internet accessible, cell signaling proteomics database (KiNET) with built in bioinformatics searching capabilities.
Kinexus claims that, KiNET is the world's only functional proteomics database available to the health care research community and features over 200,000 measurements of the expression levels and phosphorylation states of hundreds of signal transduction proteins from hundreds of different biological specimens, including over 200 tumor cell lines.
The proteins tracked in KiNET are critical for the operation of all cell and tissue types, as their malfunction has been linked to over 400 diseases including cancer, cardiovascular and neurodegenerative diseases.
Subscribing clients are able to search KiNET to plan out their next research project, discover potential drug targets and biomarkers for disease, or to better understand which pathways are regulated in response to various drugs and other treatments.
"The highly unique dataset contained in KiNET has been collected from the results of our Kinetworks™ immunoblotting services performed over the last 6 years, at a cost of over 8 million dollars," said Dr. Steven Pelech, President and Founder of Kinexus and a Professor at the University of British Columbia.
"Over 95% of the KiNET data is unpublished and not available elsewhere. It was produced in-house using the same reagents and methodology by our highly experienced scientists and technicians to ensure that it is fully comparable."
KiNET can be queried for the regulation of a target protein in hundreds of well defined experimental model systems, or a treatment or cell/tissue type can be interrogated for changes in the expression and phosphorylation of hundreds of different signaling proteins.