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Polypure Introduces Key Monodispersed Peg Compound
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Polypure has launched its latest monodispersed PEG derivative – Maleimidopropionyl-PEG NHS ester. This heterobifunctional PEG is designed to improve crosslinking between compounds carrying amino groups and thiol functions and is attracting widespread interest from both diagnostic and pharmaceutical developers.
According to Polypure Marketing Director Magali Le Bomin, this new PEG fully demonstrates the increasingly acknowledged benefits of monodispersed PEGs: “The polymer homogeneity achieved by using our patented Sample Displacement Chromatographic purification method ensures a high level of functional integrity."
"Likewise, the single molecular weight avoids the characterization problems of polydispersed polymer mixtures. Looking at applications, for diagnostics we can significantly improve cross-linking, binding and lots reproducibility. Similarly for pharmaceuticals, the extended PEG space length enhances the solubility of poorly soluble drugs," Bomin continued.
"Furthermore, there is the overriding benefit of being able to reduce diagnostic and drug design complexity which has a significant impact on development, regulatory and production times.”
