Sigma Expands Panorama™ Protein Array Product Line
Product News Feb 27, 2006
Sigma-Aldrich has announced the latest addition to its Panorama™ Protein Array product line, the Panorama™ Human Kinase v1 Array.
Developed in conjunction with Procognia Ltd, UK, and licensed exclusively through Sigma-Aldrich, the Kinase v1 protein array contains 152 commonly studied kinases.
This array is designed to employ a fusion tag attached to each kinase that serves together and uniformly orientate proteins on the array surface, and has been shown to confer kinase functionality.
This technology is designed to offer the advantage that allows proteins to behave in a sterically unencumbered manner on the array and potentially result in physiologically relevant data.
"Kinases represent a significant group of proteins within the druggable proteome and, thus, are the focus of substantial drug discovery efforts in most therapeutic areas within pharmaceutical and biotech companies, as well as academia," said Michael Hadjisavas, Global Strategic Marketing Manager for Proteomics and Cell Biology.
"Given the growing and pivotal importance of kinases in virtually every cellular function, a dire need has emerged among researchers to study the 'kinome' in a multiplex array format."
"By providing a themed array of commonly studied kinases, researchers can study the function of this key protein family by performing multiplex assays for selectivity profiling with other proteins, antibodies, peptides, kinases and drug candidates."
The Panorama Human Kinase v1 Array is designed to extend Sigma-Aldrich's array portfolio for proteomic research, including arrays of proteins, antibodies, peptides and tissue extracts.
Information on this array, as well as Sigma-Aldrich's full line of array-related products for proteomics, can be found online.