Cytokines for Stem Cell Research: Activin A, OSM, EGF, and More

Cytokines like Activin A/INHBA, OSM, EGF, VEGFA, IL3, LIF, and FGF2 play integral roles in stem and progenitor cell research. For example, OSM has been used in combination with HGF, EGF, LIF, and FGF2 to differentiate mesenchymal stem cells (MSCs) into hepatocyte-like cells. IL-3 promotes in-vitro migration of MSCs, suggesting its potential to improve the efficacy of MSCs in regenerative cell therapy. EGF has demonstrated the ability to enhance the survival of definitive neural stem cells derived from the embryonic brain. LIF is critical for regulating stem cell pluripotency, while FGF2 has been identified as a key regulator for various stem cell types.

Sino Biological offers a wide range of high-quality and GMP-grade recombinant cytokines to support stem cell research.