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LenS3 MALS Detector for GPC, HPLC and UHPLC

Tosoh Bioscience logo

The LenS3 ® MALS detector employs a novel technology for the measurement of molecular weight (MW) and radius of gyration (Rg) of synthetic polymers, polysaccharides, proteins, and biopolymers. An innovative optical design, a unique cell-block assembly, and a new calculation methodology make the LenS3 MALS detector the first groundbreaking innovation in the light scattering technology arena in decades!

With its cell geometry and a lower wavelength laser (at 505 nm), the detector allows direct measurement of molecular weight and provides best-in-class sensitivity. In addition, with an improved normalization process and a new method for utilizing the angular dependence, the determination of radius of gyration of smaller macromolecules below 10 nm in gyration size, Rg, is now possible.

The LenS3 MALS detector is driven by SECview®  software, capable of GPC system/hardware control, multi-channel data acquisition, data processing and analysis. Totally focused around enhancing the user-interface experience, SECview is a welcoming fresh perspective that streamlines the complex calculations required by the advanced detectors and is the only GPC/SEC data processing module today that performs analysis of sample-of-interest using multiple calibration methods simultaneously.


Product Specifications
Number of Measurement Angles Three (LALS -10°, RALS - 90°, HALS - 170°)
MW Range < 200 to 10^7 Da
Rg Range < 2 nm to > 50 nm (in progress)
Dimensions 36.5 (W) × 48.5 (D) × 13 (H) cm = 1.4” × 1.9” × 0.5”
Wetted Material Teflon, PEEK, Glass, Stainless Steel
Laser Power 30 mW
Laser Wavelength 505 nm
Laser Temperature Control Yes
Maximum Flow Rate 2 mL/min
About Tosoh Bioscience
By bringing the best in quality products, services and technologies from Tosoh Corporation, Tosoh Bioscience is dedicated to pioneering systems used to assist in monitoring life-threatening diseases and certain cancers, helping to prevent epidemics, purify water, monitor our environment, and making living better for everyone, everywhere.