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Neurotrophic Factors (NTFs) for Neural Cell Culture

Neurotrophic Factors (NTFs) for Neural Cell Culture


Neurotrophic factors (NTFs) control nerve cell proliferation and differentiation. The ability of these factors to promote cell survival and regeneration following injury, especially after stroke and brain injury, is applied in nerve cell culture and differentiation research. They are the first factors tested in the Central Nervous System (CNS) as therapeutic biologics.


Gradient concentrations of NTFs: NGF, NT-3, GDNF, and BDNF show the growth of neural cells in a temporospatial pattern. In addition to classical NTFs, NT-4, CDNF, MANF, NT-5, PDGF, LIF, Midkine, and the NTF receptors (TrkA, TrkB, TrkC) are in preclinical and clinical studies, with promising results in clinical trials and a few approved drugs.


Sino Biological has developed a panel of recombinant NTFs and related proteins to support the research in neurodegenerative diseases.


About Sino Biological Inc
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offers pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates