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Neurotrophic Factors (NTFs) for Neural Cell Culture
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Neurotrophic factors (NTFs) control nerve cell proliferation and differentiation. The ability of these factors to promote cell survival and regeneration following injury, especially after stroke and brain injury, is applied in nerve cell culture and differentiation research. They are the first factors tested in the Central Nervous System (CNS) as therapeutic biologics.
Gradient concentrations of NTFs: NGF, NT-3, GDNF, and BDNF show the growth of neural cells in a temporospatial pattern. In addition to classical NTFs, NT-4, CDNF, MANF, NT-5, PDGF, LIF, Midkine, and the NTF receptors (TrkA, TrkB, TrkC) are in preclinical and clinical studies, with promising results in clinical trials and a few approved drugs.
Sino Biological has developed a panel of recombinant NTFs and related proteins to support the research in neurodegenerative diseases.
Sino Biological is an international reagent supplier and contract research service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced with a stringent quality management system, and include unique bioreagents addressing areas such as cell therapy, stem cell, and infectious disease research. For example, Sino Biological has a wealth of viral antigens (Provir®) and corresponding antibodies, with one of the world’s Extensive collections. Sino Biological is also a well-recognized, qualified source of recombinant cytokines and high-quality GMP-grade cytokines. In addition, Sino Biological offers contract research production services for the custom development of full length, bioactive proteins and high-affinity antibodies, along with other services. To learn more about Sino Biological visit www.sinobiological.com, follow us on LinkedIn or @SinoInc on Twitter.
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