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Lonza

Lonza is a healthcare manufacturing organization helping pharmaceutical, biotech and nutrition companies to bring their treatments to market. They help their customers to deliver new and innovative medicines that treat a wide range of diseases, allowing their patients to benefit from life-saving and life-enhancing treatments.

Latest Lonza Content

A vial containing a DNA molecule held up.
Product News

Lonza Extends Collaboration With Major Pharmaceutical Partner for Integrated Commercial Supply of Antibody-Drug Conjugates

Lonza, announced a long-term extension of its collaboration with a major global biopharmaceutical partner for commercial-scale manufacture of ADCs.
bYlok® Bispecific Pairing Technology: A Close to Nature Solution to Overcome Chain Mispairing
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bYlok® Bispecific Pairing Technology: A Close to Nature Solution to Overcome Chain Mispairing

Lonza’s bYlok® technology addresses the challenge of heavy chain-light chain (HC-LC) mispairing in bispecific antibody production.
Three researchers in a lab.
Product News

Lonza Completes Acquisition of Large-Scale Biologics Site in Vacaville (US) From Roche

Lonza, announced it has completed its acquisition of the Genentech large-scale biologics manufacturing site in Vacaville, California (US) from Roche for USD 1.2 billion.

A DNA molecule in a glass vial.
Product News

Lonza and Vertex Sign a Long-Term Commercial Supply Agreement for CASGEVY® (Exagamglogene Autotemcel)

Lonza, a global manufacturing partner to the pharmaceutical, biotech and nutraceutical markets, announced the signature of a long-term commercial supply agreement for CASGEVY® (exagamglogene autotemcel).
Therapeutic Protein Development, Protein Expression System, Gene Expression Technology, Biopharmaceutical Manufacturing, Protein Discovery to Commercialization, Therapeutic Protein Production, Gene Expression for Biologics, Bioprocessing Solutions, GS Gene Expression System, Protein Therapeutics, Commercial-Scale Protein Production, Protein Expression Platform, Biopharma Gene Expression, High-Yield Protein Production, Biotherapeutic Development
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GS Gene Expression System®: Taking Your Therapeutic Protein from Discovery to Commercial

Lonza’s GS Gene Expression System® is a comprehensive toolbox for therapeutic protein expression, supporting the production of various molecules, including monoclonal antibodies, bispecifics, fusion proteins and beyond, with titres up to 9 g/L.
Cryopreservation infographic snippet.
Infographic

Cryopreservation: Key Principles and Recent Advances

Cryopreservation has played a critical role in biomedical research for many decades. This infographic explores some of the key principles of cryopreservation and highlights recent advances in this field.

Advances in Drug Discovery & Development 2024
Online Event

Advances in Drug Discovery & Development 2024

On-Demand
This online event is aimed at those working within academia and pharmaceutical drug development, who want to hear from experts across their field. Focus will be given to the latest advances in small molecule drug discovery and development.
Floating cells on an orange background.
Article

Challenges and Solutions in Cell Therapy Development

In this article, we explore how researchers are tackling some of the challenges preventing cell therapies from being more widely used. We also outline advances in manufacturing and regulatory approval processes that will help expand patient access to life-changing treatments.
Hepatocyte, Plateable, Induction, Drug-drug, DDI, Transporter, CYP activity, Efflux, Influx, ADME, DMPK
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Human Hepatocytes, Cryopreserved, Plateable and Interaction Qualified

Lonza's cryopreserved, plateable human hepatocytes, HUCPI, are characterized for transporter activity, enzyme activity, and enzyme gene induction potential.

Donor-matched NPCs are available. All liver-derived cells have an optimized media system for thawing, plating, and maintenance.
HUCPI
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Human Peripheral Blood Mononuclear Cells (PBMCs)

Peripheral blood mononuclear cells (PBMCs), are increasingly being used in the drug development pipeline for biological therapeutics. However, it is often difficult to align the timing of fresh leukopak availability with the availability of resources to generate experimental data, so PBMCs are usually extracted from fresh leukopaks and then frozen for later use.
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