Oxford Nanopore Technologies

Take your sequencing to the next level with the recently released PromethION 2 devices. They enable flexible, high-yield sequencing, in a compact, accessible design.

Over recent years, genomic sequencing of pathogens has emerged as a powerful tool to guide public health action by providing a deeper understanding of pathogen evolution, emerging variants and transmission dynamics. Oxford Nanopore Technologies offers an accessible, all-in-one sequencing platform that enables rapid, distributed and scalable genomic pathogen surveillance.

In this webinar, you will hear from leaders in the field of microbiology and infectious disease research, who will share their experiences in developing and implementing fast and accessible pathogen surveillance protocols with nanopore sequencing. The protocols presented in this webinar can be leveraged for targeted whole genome sequencing of different viral pathogens such as SARS-CoV-2 and monkeypox virus, as well as more broadly for the genomic characterization of known and novel viruses in an untargeted manner.

The genetics behind cancer are both diverse and complex, with many abnormalities causing, contributing, or indicating the disease. Using nanopore sequencing, scientists can resolve variants and epigenetic modifications across the entire genome, target large panels or single genes, and detect known and novel full-length transcripts – for the most comprehensive insight into cancer genomes.

Our major findings were that the neural network was able to accurately classify 11 out of 12 leukemia samples, with as little as 5 minutes of sequencing needed to accurately classify ALL.

The last twenty years have experienced extensive growth in the sequencing of cancer genomes, leading to a dramatically increased understanding of the role of genetic and epigenetic mutations in cancer.

It’s possible to target regions of DNA in real time using adaptive sampling on nanopore devices. The nanopore has the ability to read the strand sequence in real time, if it is not the strand of interest, the strand is ejected, but if it is, the nanopore recognises this and continues to read the strand. Researchers then get more of the sequence they are interested in within a shorter period of time, allowing faster and easier analysis.

Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours.

Oxford Nanopore launched ORG.one to support faster, more localised sequencing of critically endangered species.

In this webinar, New York University’s Dr. Jae Young Choi will discuss how to perform Pore-C sequencing in plant species to generate chromosome-level genome assemblies and map chromatin interactions to identify candidate enhancer‒gene interactions.

A new ultra-rapid genome sequencing approach developed by scientists has been used to diagnose rare genetic diseases in an average of eight hours.