Advanced Cell Models – News and Features

UC researchers reveal that miR-205 regulates MED1 and HER3, proteins driving breast cancer treatment resistance. Boosting miR-205 levels could block MED1 production and activity, enhancing therapy outcomes.

For the first time, researchers have cultivated stable tumor organoids from circulating breast cancer cells, improving research into therapy resistance.

Researchers have developed a new way to grow organoids using Invasin, a bacterial protein.

Yale researchers discovered that an underactive mTOR pathway drives structural malformations in lissencephaly. They showed that activating the mTOR pathway prevents and reverses thickened cortical structures.

Stem cell-derived brain organoids sent to the International Space Station matured faster than identical organoids on Earth, potentially shedding light on the neurological effects of space travel.

University of Wisconsin–Madison researchers revealed how gut microbial bile acids impact colon cancer. One bile acid slows tumor growth by supporting the FXR protein, while another accelerates cancer by inhibiting it.

Researchers find answers to why older people had a somewhat reduced immune response to the mRNA vaccines administered during the COVID-19 pandemic when compared with younger adults.

A new imaging technique can more than double the usual depth limit of metabolic imaging, yielding richer and more detailed images.

This article explores some of the challenges in developing cell lines for therapeutics, such as cell line stability, and how they are being addressed.

Researchers discovered that a fetus has a functional immune system that is well-equipped to combat infections in its developing nervous system, long before birth.