Advanced Cell Models – News and Features

Have you ever wondered why dogs and cats can only see a limited color spectrum, while humans are able to envision a spectrum that is millions of colors-wide? Researchers from John Hopkins University set out to understand this phenomenon.

Researchers have now identified the protein EPAC1 as a new pharmacological target to increase brown fat mass and activity. The long-term aim is to find medicines that support weight loss.

Organoid research at the Department of Life Sciences shows how a gene mutation slows down stem cell differentiation, setting the scene for age-related disease.

Getting the right amount of folic acid intake is important for women who are planning to become – or are – pregnant. A new study in mice suggests excessive folic acid, and low vitamin B12, could cause adverse changes in neuronal development.

Mayo Clinic researchers mapped how the measles virus mutated and spread in the brain of a person who succumbed to a rare, lethal brain disease.

Human organ chip research shows that a common antimalarial combination could reverse the negative effects of malnutrition in the female digestive tract that lead to low birth weight infants.

Researchers have explored what happens when functional vasculature is added to cerebral organoids, illustrating the effects of vascularization on cell populations.

Researchers at the National Institutes of Health have mapped the 3D organization of genetic material of key developmental stages of human retinal formation, using intricate models of a retina grown in the lab.

Researchers have developed new virtual reality (VR) goggles for mice, advancing accurate and precise behavioral research by simulating natural environments.

Researchers from Japan have created a pancreatic ductal adenocarcinoma (PDAC) organoid model using human-induced pluripotent stem cell (hiPSC) technology, simulating desirable TME properties.