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Advanced Cell Models – Webinars and Online Events

Webinar

Retinal Organoids as an Emerging Tool for Drug Discovery

On-Demand
Human induced pluripotent stem cell (iPSC)-derived retinal organoids are an emerging tool for the study of retinal development, disease modeling and drug discovery.
Webinar

Bringing Life to PK Profiles – In Vivo-Relevance From an In Vitro Environment

On-Demand
In drug development, microphysiological systems (MPS) are utilized to develop in vitro biological models that can generate more physiologically- and human-relevant data.
Webinar

Formulating a New Approach to Pharmacokinetics and Cell State Control

On-Demand
Most in vitro, well-plate biological experiments require a media change every day or two, with cyclic variations in nutrient and metabolite concentrations leading to physiologically unrealistic gene expression and metabolism.
Webinar

Pathologically Scarred by Fibrosis: How To Model and Quantify Human NASH in a Microphysiological System

On-Demand
In this webinar, we will demonstrate how an advanced three-dimensional (3D) microfluidic model of non-alcoholic steatohepatitis (NASH) can be fine-tuned using exogenous stimuli to enhance key features such as fibrosis or inflammation.
Webinar

Towards a Body-on-a-Chip: The Value of Multi-Organ MPS for Human-Relevant Drug Assessment

On-Demand
Microphysiological Systems (MPS), also known as organ-on-a-chip, generate human-relevant 3D cell culture models whose phenotypes and functions mimic individual in vivo organs. When therapeutics are added, these models can generate results that translate into clinical outcomes more reliably than standard in vitro techniques.
Webinar

Engineering Mucosal Barriers: From Organoids to Organs-on-Chips

On-Demand
Mucosal barriers are the gateways to all internal organs, serving to transport oxygen, nutrients, and waste and at the same time performing enormous feats of protection against infection and other hazardous insults. The explosion of interest in the human microbiome – especially but not only that in the gut – has driven new interest in building human mucosal barrier models.
Webinar

A Microphysiological Model of Metastatic Progression

On-Demand
Metastatic disease is the leading cause of mortality in patients with solid tumors. Despite decades of research, we only partially understand the underlying cellular and molecular mechanisms.
Webinar

Testing on Humans: How To Predict Hepatotoxicity and Drug Clearance Ahead of Clinical Trials Using Liver-on-a-Chip

On-Demand
Current in vitro approaches for investigational toxicology, drug metabolism (DMPK) and safety are limited and are not fully representative of human response; therefore, drugs showing acceptable preclinical toxicity often fail in human clinical trials, and accurately predicting human drug exposure for new compounds is challenging and costly.
Webinar

The Rhythm of Life: Using Microfluidics To Mimic Blood Flow in Single- and Multi-Organ-on-a-Chip Models

On-Demand
Microphysiological systems (MPS), or organ-on-chip (OOC) technologies, enable researchers to model human biology in the lab via 3D microtissue-based studies.
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