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Anticancer Therapies – News and Features

An IV inserted into a hand.

Drug Targeting “Stressed” Cancer Cells Shows Promise in Trial

In a clinical trial, a new drug prevented cancer growth in terminally ill patients, with 70% of those who received the medicine becoming stable after six weeks.
A person walking with gym shoes on.

Physical Activity May Prevent Colon Cancer Returning

New research has found that physical activity can prevent, and not just delay, cancer recurrence in patients previously treated for colon cancer.
Microscope image of a group of killer T cells (green and red) surrounding a cancer cell (blue, center).

Could Lymph Nodes Improve Cancer Immunotherapy Success?

New data suggests immunotherapies may activate lymph nodes to produce tumor-fighting T cells.
Abstract pink and orange bubbles.

Nanotechnology Could Aid Drug Delivery for Lymphedema

By using nanotechnology to repair the pumping action of lymphatic vessels, Georgia Institute of Technology researchers have developed a unique approach to treating lymphedema.
Disc-shaped 3D scaffolds that mimic bone structure and texture.

Improved Bone Tumor Model Boosts Search for Therapies

Researchers have developed and used an upgraded tumor model that mimics bone to find that the body’s immune response can make tumor cells more resistant to chemotherapy.
Representation of human cells.

Key Source of T-Cell “Exhaustion” Identified

In a new study, scientists show the commanding role of a specialized group of proteins in the nuclei of our cells, called mSWI/SNF (or BAF) complexes, both in activating T cells to attack cancer and triggering exhaustion.
A picture of the human body focusing on the pancreas.

New Biomarkers Could Be “More Accurate” Predictors of Pancreatic Cancer

A new study identifies a set of biomarkers that could help clinicians to predict whether pancreatic cysts will remain benign or develop into cancer.
Immunofluorescent image taken under the microscope of Sotorasib-resistant lung cancer cells displaying multiple copies of the mutated KRAS gene (in red).

Resistance Mechanisms to KRAS Inhibitor in Lung Cancer Identified

A new study reveals the mechanisms responsible for the development of tumor resistance to a new drug, the first approved inhibitor against the KRAS oncogene.
A before and after photo of lung tissues treated with the novel drug combination.

New Drug Combination Reduces Lung Tumors in Mice

A targeted therapy that combines two different drugs has been shown to be effective at reducing the size and number of non-small cell lung cancer tumors in mice.
White pills of different shapes and sizes in their packets.

How a Class of Cancer Drugs Causes Inflammatory Side Effects Discovered

The mechanism behind how tyrosine kinase inhibitors – a class of cancer drug – cause serious inflammatory side effects has been revealed by a new study.