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Biomarkers – Multimedia

Expression of Wnt5a in Urothelial Carcinoma as a Potential Prognostic Marker content piece image
Poster

Expression of Wnt5a in Urothelial Carcinoma as a Potential Prognostic Marker

Our results support the previous studies that suggest Wnt5a plays a pathological role in urothelial carcinoma.
Expression Profiling of Circulating Tumor Cells: a Prognostic and Predictive Biomarker in Cancer. content piece image
Poster

Expression Profiling of Circulating Tumor Cells: a Prognostic and Predictive Biomarker in Cancer.

We show non-responders to treatment among breast cancer patients can be identified by expression profiling of circulating tumor cells
Low-cost Electrochemical Microfluidic Immunoarrays for Cancer Diagnostics content piece image
Poster

Low-cost Electrochemical Microfluidic Immunoarrays for Cancer Diagnostics

This poster describes the development and validation of a simple, low-cost, semi-automated microfluidic device for cancer biomarker protein detection to aid in cancer diagnosis and therapy monitoring.
Searching for Urinary Biomarkers of Exposure to Heterocyclic Amines (HCAs) content piece image
Poster

Searching for Urinary Biomarkers of Exposure to Heterocyclic Amines (HCAs)

Heterocyclic amines (HCAs) are foodborne carcinogens present in cooked meat and fish, mainly. Metabolites of HCAs have been determined in urine from volunteers following a controlled meal.
PRESEPSIN, A SOLUBLE CD14-SUBTYPE, A POSSIBLE NEW BIOMARKER INCREASES IN SEPTIC PATIENTS’ PLASMA FROM PEDIATRIC DEPARTMENT. content piece image
Poster

PRESEPSIN, A SOLUBLE CD14-SUBTYPE, A POSSIBLE NEW BIOMARKER INCREASES IN SEPTIC PATIENTS’ PLASMA FROM PEDIATRIC DEPARTMENT.

Increased plasma concentration of soluble CD14-subtype (presepsin) was observed in pediatric patients with bacteremia. Presepsin could be a possible biomarker of sepsis in pediatric patients, however, their reference interval in children could be lower than that of adults. More studies with larger number of samples are required to confirm the result.
Video

Magneto-plasmonic Nanoparticle Platform for Capture, Separation and Enumeration of Rare Cells

In this presentation we will explore the opportunities afforded by the hybrid magneto-plasmonic nanoparticles and PA imaging for the development of a low cost simple and nearly real-time assays for capture, separation and enumeration of rare cells.
On-chip quantification of miRNA using digital droplet PCR content piece image
Poster

On-chip quantification of miRNA using digital droplet PCR

miRNAs have a great potential in diagnostics. Hence, automated profiling of miRNAs are of great interest. In-house technology show that it is possible to implement a multiplexing assay for miRNAs on a microfluidic chip using digital droplet PCR.
Video

Microfluidic Systems for Biomarker Analysis and Cancer Diagnosis

In this talk, Martin Gijs discusses a novel magnetic surface coverage assay and a microfluidic tissue processor with applications in cancer diagnostics.
A multianalyte algorithm PCR-based blood test outperforms single analyte ELISA-based blood tests for neuroendocrine tumor detection content piece image
Poster

A multianalyte algorithm PCR-based blood test outperforms single analyte ELISA-based blood tests for neuroendocrine tumor detection

In a prospective study, in age-/sex- and ethnicity-matched patients and controls (n=82), a 51 panel multigene blood transcript test (NETest) was identified to be significantly more sensitive and accurate (>93%) than any single analyte assay (Chromogranin A, Pancreastatin or Neurokinin A) for neuroendocrine tumor detection.
App Note / Case Study

Automating ELISAs on Tecan’s Freedom EVO® using Optimiser™ technology from Siloam Biosciences

One of the challenges in life sciences research today is to discover methods for running key assays more quickly, more reliably and using lower volumes of reagents and sample, but still with improved sensitivity. One area where this particularly holds true is for traditional enzyme-linked immunosorbent assays (ELISAs), whose application provides a useful measurement of antigens, including cytokines and a host of other biomarkers.
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