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Cancer Diagnostics – Multimedia

6 Microfluidic Researchers You Should Follow content piece image
Listicle

6 Microfluidic Researchers You Should Follow

In this list we take a look at 6 researchers whose contributions have helped (and are continuing to help) drive the field forward.
Eight Emerging Applications of Mass Spectrometry content piece image
Listicle

Eight Emerging Applications of Mass Spectrometry

This article highlights some of the wide range of applications which can be achieved using mass spectrometry.
Is Oxford Nanopore Technology Ready for Clinical Diagnostics? content piece image
Poster

Is Oxford Nanopore Technology Ready for Clinical Diagnostics?

Our objective is to validate diagnostic services using Oxford Nanopore’s Minion in the first instance and to evaluate the cost and performance compared to existing sequencing technology in areas such as tumour DNA sequencing (and circulating tumour DNA), virology, microbiology, genetics and HLA-typing.
App Note / Case Study

Gold Nanoparticle Applications and Characterization by Nanoparticle Tracking Analysis

Gold nanoparticles are one of the most popular and extensively researched type of nanoparticle.
A Novel Cell-Free DNA Extraction System for Cancer Diagnostics content piece image
Poster

A Novel Cell-Free DNA Extraction System for Cancer Diagnostics

We developed a magnetic bead-based cfDNA extraction kit and integrated it into the automated qPCR- and NGS-based IVD workflows. In this study we are compering this magnetic beads-based cfDNA extraction system with a column-based method.
Clinical Applications of “Liquid Biopsy” in the Colorectal Cancer Treatment content piece image
Poster

Clinical Applications of “Liquid Biopsy” in the Colorectal Cancer Treatment

Liquid biopsy provides a circulating biomarker not only for treatment response but decision making of a sequential strategy.
Minimizing Carry-over for High Throughput Analysis content piece image
Poster

Minimizing Carry-over for High Throughput Analysis

Minimal carry-over is a prerequisite for high throughput analysis. However, minimized carry-over and cycle time are competing and a careful optimization is mandatory. In this study the influence of wash conditions on carry-over of various compounds was investigated. A strategy to minimize carry-over was developed. The influences of different wash tasks were investigated. Finally the contribution of different system components such as injector valve or column was studied.
Automated In-gel Digestion on a Commercial Autosampler Directly Coupled to Nano LC-MS/MS content piece image
Poster

Automated In-gel Digestion on a Commercial Autosampler Directly Coupled to Nano LC-MS/MS

SDS-PAGE separates protein samples from LC-MS incompatible contaminations, and is frequently used to fractionate proteins of entire proteomes. One disadvantage is that gel lanes have to be cut into many slices, followed by in-gel digestion of proteins and extraction of peptides. The number of these gel slices goes into the hundreds, rendering this process very repetitive and prone to mistakes and errors during sample handling. Automation reduces such risks and improves reproducibility.
App Note / Case Study

Proteomic Analysis of Laser Microdissected FFPE Tissue Using Mass Spectrometry

This application note discusses a study which was undertaken to identify candidate protein biomarkers for early detection of endometrial cancer using formalin fixed paraffin embedded tissue samples.
Video

SPR Imaging-based Microarray for Enhanced Multianalyte Detection in Blood Plasma

Marketa Bockova, Institute of Photonics and Electronics ASCR, speaking at Biodetection & Biosensors 2015
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