Cancer Genetics – News and Features

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Machine Learning-Powered Blood Test Enables Detection of Multiple Cancers
A new machine learning-powered blood test can detect multiple types of cancer in their earliest stages.

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AI Tool Can Predict the Activity of Genes Within Any Human Cell
A new AI tool can accurately predict gene activity within any human cell, revealing the cell's inner mechanisms.

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Sweet Spot of Mitochondrial Mutations Fuels Cancer Growth
St. Jude researchers reveal that moderate levels of mitochondrial DNA mutations boost leukemia growth by increasing metabolic plasticity, while high mutation levels shut down tumor development.

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Chemical Processing Found To Deplete Nutrients in Plant-Based Drinks
A study by the University of Copenhagen reveals that plant-based drinks, like almond and oat milk, lack essential proteins and amino acids compared to cow’s milk. Extensive processing, including UHT treatment, reduces nutritional quality.

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Study Reveals Nutritional Gaps and Health Concerns in Plant-Based Drinks Compared to Cow’s Milk
A new study of plant-based drinks shows they lack proteins and essential amino acids compared to cow’s milk due to extensive processing, which degrades protein quality and can create harmful substances.

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FDA-Approved Drug Shows Promise in Advanced NSCLC
A UT Southwestern trial found selinexor, an FDA-approved drug, effective in KRAS-mutated non-small cell lung cancer (NSCLC). Combined with chemotherapy, it achieved tumor control in 80% of cases.

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Widely Used Herbicide Linked to Alzheimer’s-Like Brain Damage
A study from Arizona State University links glyphosate, a widely used herbicide, to Alzheimer’s-like brain damage and persistent neuroinflammation in mice. Findings show lasting effects even at regulatory "safe" doses.

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Research Helps Explain Why Cancer Risk Declines After Reaching Advanced Age
MSK researchers discovered that aging cells mimic iron deficiency, reducing their ability to regenerate and develop cancer. However, this also makes older cells more resistant to therapies like ferroptosis.

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Mechanisms That Make Ewing Sarcoma More Aggressive Discovered
A study from Spain’s CNIO identifies genetic alterations linked to STAG2 loss, driving aggressiveness in Ewing sarcoma. These changes increase metastasis and impact immune response, offering new prognostic markers and therapeutic targets.

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Cancer Researchers Think They Now Know Why Immune Checkpoint Inhibitor Therapies Increase Infection Risk
Researchers revealed that checkpoint inhibitors, a powerful cancer immunotherapy, impair B cell function, reducing antibody diversity and increasing infection risk. They suggest immunoglobulin replacement therapy as a preventive measure.
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