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Cancer Immunology – News and Features

3D illustration of CAR T cells attacking a cancer cell, highlighting cellular aging processes.
News

CAR T-Cell Aging Linked to Cancer Relapse

Researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR T-cell therapy. Over time, the engineered immune cells age and lose their ability to fight cancer.
Illustration of multiple orange/red cancer cells.
News

Disrupting the Cell Feedback Loop Fueling Leukemia

Researchers have identified a signaling loop involved in the growth and persistence of leukemia cells, and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival.
3D illustration of antibody and virus particles highlighting glycan structures for glycan analysis.
Article

A Guide to Glycan Analysis of Therapeutic Glycoproteins

Discover what glycan analysis can reveal about protein behavior and how it can be used to boost biologic performance and ensure therapeutic quality in biopharmaceutical drug development.
Woman sneezing into a tissue outdoors, showing symptoms of hay fever during allergy season.
News

“Molecular Shield” in the Nose Blocks Hay Fever Reactions

Researchers developed a nasal antibody that blocks mugwort pollen, a major hay fever trigger in Europe and Central Asia. Delivered intranasally, it reduced allergic symptoms and inflammation in mice without systemic side effects.
A row of vaccine vials for holding cancer vaccine with blue tops.
News

Updated Personalized Cancer Vaccine Generates Strong Immune Response

Results of a phase 1 clinical trial for patients with melanoma show that an updated formula and delivery of the NeoVax personalized cancer vaccine is safe, feasible and improves the vaccine-specific immune response generated.
Immunohistochemistry slide of cancer tissue viewed under a microscope.
News

Pre-Surgery Immunotherapy Keeps 80% of Advanced Melanoma Patients Disease-Free

Four years after pre-surgery treatment with a novel combination of immune checkpoint inhibitors, nivolumab and relatlimab, 87% of patients with stage III melanoma remained alive.
Woman wearing orange hoodie running.
News

Gut Microbes Key in Exercise's Cancer-Fighting Effect

A new study, for the first time, shows how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome.
3D illustration of immune cells attacking a cancer cell, representing cancer immunotherapy.
News

Repurposed Drug May Reduce Cancer Immunotherapy Side Effect

A team of researchers has identified a potential new strategy to prevent, or even reverse, immune checkpoint inhibitor–induced type 1 diabetes.
3D illustration of immune cells attacking a cancer cell, representing the mechanism of cancer immunotherapy.
Article

The Immune System in Cancer: Its Roles and How We Can Harness It

This article explores the relationship between the immune system and cancer and outlines therapeutic strategies that leverage a patient’s immune system to treat cancer.
X-ray image of patient with lung cancer.
News

Corticosteroids Shown To Weaken Effectiveness of Immunotherapy

A new study showed that high doses of steroids, when given before and/or during a specific type of immunotherapy, caused patients’ tumors to shrink less than those of patients not on steroids. Those patients also did not live as long.
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