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Cancer Immunology – News and Features

Illustration of microscopic cancer cells.
News

Personalized Cancer Vaccines Slow Tumor Recurrence in Mice

Using a newly discovered byproduct of dying cancer cells, University of Wisconsin–Madison researchers are developing personalized vaccines that could help keep aggressive tumors from recurring.
White blood cells attacking cancer cell, indicating cancer immunotherapy.
News

Enabling the Body To Engineer Its Own CAR T Cells

A new approach induces the patient’s body to produce its own CAR-T cells, relying on the same messenger RNA (mRNA) technology that was instrumental for some COVID-19 vaccines.
Illustration of microscopic red cancer cells.
News

Key B-Cell Lymphoma Traits Linked With Greatest Benefit From CAR T-Cell Therapy

In the largest study of its kind, researchers from The University of Texas MD Anderson Cancer Center identified three subgroups of patients with large B-cell lymphoma who have different levels of benefit from CD19 CAR T-Cell Therapy.
Illustration of modified microscopic red cells, indicating cell therapies.
News

First Use of CAR T-Cell Therapy for Autoimmune Neuropathy

A team of physicians from Bochum are the first to successfully use CAR T-cell therapy to treat two patients with a rare autoimmune disease of the peripheral nervous system.
A scientist pulling out a blood sample vial from a test tube rack.
News

Blood Test May Help Detect Liver Transplant Issues Early

Studying the chemical signatures of DNA fragments in the blood could help scientists pinpoint the cause of organ damage post-transplant, without the need for costly imaging studies or invasive biopsy tests.
An example of a monoclonal antibody such as pembrolizumab, which wasn't recently approved for treating head and neck cancer.
News

FDA Approves Pembrolizumab for Advanced Head and Neck Cancer

Pembrolizumab, an immune checkpoint inhibitor, has been approved by the US Food and Drug Administration for the treatment of patients with resectable locally advanced head and neck squamous cell carcinoma whose tumors express PD-L1.
Blue immune cells attacking a yellow cancer cell in cancer immunotherapy.
News

New Method Helps Track Immune Cells During Immunotherapy

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets. Researchers have now developed a method for tracking these cells in the body.
Neurons with amyloid plaques, which are implicated in Alzheimer's disease pathology.
News

The Same Technology Used in Cancer Immunotherapy Could Help Target Alzheimer’s

Inspired by cancer immunotherapy, scientists engineered immune cells equipped with specialized targeting devices called chimeric antigen receptors (CARs) that can distinguish and respond to tau tangles and various forms of toxic amyloid plaques.
Illustration of pink/orange cancer cells dividing.
News

EGFR Inhibitors as a Solution for NF1-Mutant Melanoma

Increased activity in a specific biological pathway may explain why many patients with a deadly form of skin cancer do not respond to the latest cancer treatments, a new study shows.
Illustration of microscopic red cancer cells.
News

A New Tumor-Targeting System for Cancer-Fighting Cells

Researchers have developed new CAR-T cells to target malignant tumors. Their method targeted a protein found in high amounts on many types of cancer cells (Eva1) and successfully eliminated tumors in lab mice.
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