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Cancer Immunology – News and Features

Cancer cells.
News

New Potential Target for Leukemia Therapy Identified

A team of Dana-Farber Cancer Institute investigators discovered that a subset of myeloid and lymphoid leukemias depend on a molecular complex called PI3Kgamma for survival.
immunofluorescent staining shows a lymph node that has been significantly expanded in mice with the help of the biomaterial MPS-vaccine (on the right), next to a lymph node taken from non-treated control mice (on the left) at the same time post-vaccination.
News

Biomaterial Vaccine Enhances Lymph Node Expansion and Boosts Anti-Tumor Immunity

A biomaterial vaccine enhances and sustains lymph node expansion following vaccination, boosting anti-tumor immunity in an animal model.
Cancer cells.
News

Study Uncovers a Cause of Cancer Immunotherapy Roadblocks

A study led by Yale scientists, investigated the potential causes associated with T cell exclusion using a genome-wide screen of more than 1,000 human proteins.
Cancer cells.
News

Novel Combination Therapy Shows Promise for Liver Cancer

A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without compromising their safety.
A needle inserted into a vaccine vial.
News

Experimental mRNA Brain Cancer Vaccine Evaluated in Small Trial

A new mRNA vaccine has shown promise in activating the immune system against a highly lethal type of brain tumor, according to results from a first-in-human clinical trial of four adult patients with glioblastoma.
Cancer cells.
News

Pancreatic Cancer Cells Differ by Location and May Inform Targeted Treatments

A new study has found that pancreatic cancer cells are different based on their location in the pancreas, providing new information about tumors that could lead to better targeted treatments.
A drip bag of medication on a stand.
News

Regulating Cholesterol Levels Could Improve Cancer Immunotherapies, Study Finds

New research has identified that regulating cholesterol levels can help make existing cancer treatments more effective by regulating a critical immune pathway.
Epstein-Barr virus (EBV) stained with Hematoxylin and eosin (HE)
Article

Epstein-Barr Virus, Multiple Sclerosis and Cancer: Looking Back at 60 Years of Research

In this interview, Professor Lawrence Young discusses the current interest in Epstein-Barr virus (EBV) vaccines for combatting multiple sclerosis and his thoughts on the future direction of EBV research.
A scientist holds a vial of blood in a gloved hand.
Article

Advances in Liquid Biopsies: Improving Sensitivity and Earlier Detection

This article will focus on some of the advances currently being made in the field of liquid biopsy, from attempts to improve the sensitivity of tests, to using bodily fluids other than blood.
Cancer cells.
News

Biomarkers Linked to Cell Therapy Response for Bone Marrow Tumors Identified

In a recent clinical study, researchers identified several biomarkers that are associated with the response to CAR T cell therapy in multiple myeloma, a malignant tumour disease in the bone marrow.
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