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Cell Culture – News and Features

A 3D model of a human kidney.

Lab-Made Kidneys Grown With Blood Vessels for the First Time

For the first time scientists managed to generate kidney organoids with a complex vascular system. These are asembloids, micrometric organoids formed by the union of kidney organoids with vascular organoids in 3D.
Double helix structure of DNA.

Ancestral Differences Affect Performance of CRISPR-Cas9 Guides in Human Cells

New research shows that many of these CRISPR screening experiments rely on components, called CRISPR/Cas9 guides, that do not perform equally well in cells from people of all ancestries, which can cause CRISPR screens to miss cancer dependencies.
A puzzle that spells the word autism.

Brain Cell Overgrowth Before Birth Associated With Autism Severity

Brain organoids derived from toddlers with autism spectrum disorder suggest that subtypes of the condition may have in utero origins. That's according to a new study from researchers at the University of California San Diego, led by Dr. Alysson R. Muotri.
Cancer cells.

Gene Identified That Helps Cancer Cells Spread Around the Body

Investigators have identified a gene whose expression confers a growth advantage to metastatic cancer cells, which cause 90% of cancer-related deaths. Silencing this gene in lab models of cancer prevented metastatic cells from growing and spreading.

Human Derived RNA Integration Fuels Chronic Hepatitis E Virus Infection

Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year.
Page of a calendar showing a month with three consecutive Saturdays circled.

The Friedman Test

The Friedman test can be used to compare repeated measures or samples, such as following a person's biological functions over time. In this article, we consider its assumptions, when to use it and go through a worked example.

ARRALYZE glass array with three different shaped wells highlighted. Each well is enlarged to display a different type of cell.
Industry Insight

Navigating the Complexities of Single-Cell Research

The advent of single-cell analysis has marked a transformative era in the life sciences, particularly in the field of drug development. To delve deeper into the subject, Technology Networks spoke with Dr. Nora Fekete-Drimusz, head of biology at ARRALYZE. We discuss the transformative impact of single-cell analysis on life science research and explore how ARRALYZE's multifunctional single-cell platform can support those working in this area.
Bacteria in an intestine.

Novel Antibiotic Kills Pathogenic Bacteria but Spares Healthy Gut Microbes

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.
Floating cells on an orange background.

Challenges and Solutions in Cell Therapy Development

In this article, we explore how researchers are tackling some of the challenges preventing cell therapies from being more widely used. We also outline advances in manufacturing and regulatory approval processes that will help expand patient access to life-changing treatments.
A futuristic-style illustration of a trophy on a dark blue background.
Industry Insight

SLAS Europe 2024 New Product Award: Top Contenders Announced

Finalists for the New Product Award at the SLAS Europe conference showcase cutting-edge innovations in life sciences, evaluated on technical merit, commercial feasibility, originality, impact and market opportunity. Here, we take a look at the six nominees and the products competing for this year’s award.