Cell Culture – News and Features

A new study reveals the Zika virus’s infectious success: Zika uses host cells’ own “self-care” system of clearing away useless molecules to suppress the host proteins that the virus has employed to get into those cells in the first place.

Researchers have developed the first vascularized organoid model of pancreatic islet cells, which promises to improve diabetes research and cell-based therapies.

Researchers have developed a new gene therapy that can be delivered using a nasal spray, ensuring that the therapeutic is efficiently delivered to where it is needed in the lungs and airway.

Axolotl limbs regenerate functional body parts in just weeks, relying on cells that retain positional memory. The Hand2 gene marks the posterior side of the limb and controls the activation of the Shh signaling pathway after injury.

Researchers have identified flavonoids toxic to bladder cancer cells cultured in the lab. Cell Painting technology enabled them not only to identify anticancer compounds but also to uncover insights into their mechanism of action.

Medulloblastomas are one of the most common childhood brain cancers. University of Michigan researchers have now identified a new target for Group-3 medulloblastomas. The results help identify new therapeutic avenues for treating these deadly tumors.

A study from NTNU reveals that JAK inhibitors, prescribed for autoimmune diseases like rheumatoid arthritis, may suppress the body’s antiviral defenses, making patients more vulnerable to viruses like influenza and SARS-CoV-2.

Scientists have developed an advanced gene editor – the evoCAST – that can add long stretches of DNA to defined locations in the human genome without creating unwanted modifications.

Researchers have created a groundbreaking 3D-printed artificial tumor tissue capable of replicating the in vivo conditions of patient-derived cancer cells, which can be used to predict prognosis.

Researchers have completed the full genome of the northern white rhinoceros, aiding efforts to rescue the functionally extinct species. The high-quality reference genome enables quality control of stem cells intended to create sperm and eggs.